The UK RDM club (run by our wonderful project partners ELIXIR-UK) is a monthly meeting held over zoom on the first Tuesday of every month, with a focus on ELIXIR-UK activities that help people manage their life science research data. They welcome participation from data stewards, support staff and researchers interested in Research Data Management (RDM) in the life sciences. In this RDM Club Call, Gavin Farrell (ELIXIR Ireland), a contributor to ELIXIR’s AI Ecosystem Focus Group work, will introduce the concept of Open and Sustainable AI (OSAI). Grounded in the ELIXIR Europe Machine Learning Focus Group work that culminated in the 2025 preprint Open and Sustainable AI: challenges, opportunities and the road ahead in the life sciences, the talk presents nine OSAI guidelines for ensuring AI datasets and models can be reused and reproduced while also supporting environmental sustainability.